Phenylalanine Kit(FA)

2017-08-29

　　Generic Name: phenylalanine quantitative detection kit (fluorescence method)

　　English name: Phenylalanine Kit (FA)

　　[Medical Device Manufacturing Enterprise License No.】 Beijing Drug Administration firearms production Xu 20,040,085 No.

　　[Medical Device Registration Certificate No.] SFDA (Approved) 2009 The number 3400174

 

▲ Product name

　　Generic Name: phenylalanine quantitative detection kit (fluorescence method)

    English name: Phenylalanine Kit (FA)

    [Medical Device Manufacturing Enterprise License No.】 Beijing Drug Administration firearms production Xu 20,040,085 No.

    [Medical Device Registration Certificate No.] SFDA (Approved) 2009 The number 3400174

 

▲ Packing

        96 / box, 480 / box

 

▲ intended use

    For the quantitative determination of the concentration of newborns collected on filter paper S & S 903 # whole blood samples phenylalanine. Suitable for newborns for phenylketonuria (PKU) screening, only for in vitro testing.

 

▲ Applicable models

    Finnish company WALLAC 1420 PE fluorescence analyzer (excitation wavelength 390nm, emission wavelength 486nm).

 

▲ Products

Children Urine enzyme phenylalanine metabolic pathway caused by defects in benzene emit large amounts of metabolites phenylalanine disease, known as phenylketonuria, it is an autosomal recessive genetic disease. Phenylalanine hydroxylase is a special liver enzyme that congenital deficiency or decreased activity not normally lead to hydroxylation of phenylalanine to tyrosine, but into the human circulation, making the blood, cerebrospinal fluid and urine of benzene alanine increased. The disease is often accompanied by inhibition of tyrosinase tyrosine metabolism.

Phenylalanine, phenylpyruvic acid, phenylacetic acid accumulation can cause brain and other developmental disorders, myelination blocked, gray degeneration, and causes mental retardation in infants, often occurs before the age of seizures, infantile spasms and even have similar Clinical manifestations of disease and EEG peak imperfectly, children may also have movement disorders, cerebral palsy, hyperactivity, tremors and vomiting, anxiety, eczema and other symptoms.

Neonatal screening for early detection of phenylalanine in children, and in a timely manner a low-phenylalanine diet therapy, so that children maintain blood phenylalanine at 1-2mg / dl, thereby preventing severe mental disorders and continue the occurrence of idiopathic epilepsy and other diseases, has important clinical significance.